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I.V. League Hydration

Cellular Wellness · South Boston

NAD+ IV Therapy in Boston

Restore cellular energy, cognitive clarity, and recovery capacity. Medically supervised NAD+ protocols starting at $425.

South BostonMedically SupervisedNurse-Owned Since 2018

Medically directed and founded by Olivia Kelly, NP, NP, RN — Licensed since 2003.

NAD+ is the master coenzyme powering energy production and DNA repair in every one of your cells. Levels decline sharply with age, stress, and disease — and low NAD+ shows up as fatigue, brain fog, poor sleep, slower recovery, and accelerated aging. IV NAD+ therapy delivers a therapeutic dose directly to your cells for measurable results in 24–72 hours. IV League's NAD+ protocols are designed by NP Olivia Kelly and administered led by our Medical Director Olivia Kelly, NP.

Related reading

Myers Cocktail vs NAD+ IV: what's in a Myers Cocktail and who it's for

Deciding between NAD+ and the classic Myers Cocktail IV? Compare ingredients, benefits, and how long each drip lasts.

Compare

NAD+ IV vs. injections vs. oral supplements

All three raise NAD+ — they differ in how much reaches your cells and how fast you feel it.

MethodTypical doseTimeAbsorptionBest for
NAD+ IV infusion250mg60–90 min100% bioavailableLoading phase, biggest and fastest effect
NAD+ IM / SC injectionLower dose~10 minHighWeekly maintenance between infusions
Oral NR / NMN capsulesPrecursor onlyDailyLimited by first-pass metabolismBetween-visit top-up, not a replacement

Pricing

Transparent pricing

NAD+ IV — 250mg

$425

Single infusion — 60–90 min

NAD+ Loading Package

$1,600

4 infusions — save $100

NAD+ IM/SC Injection

Ask

Faster in-and-out option, weekly

HSA/FSA accepted. Ask about membership pricing.

Benefits

Why patients choose NAD+ IV therapy

Cellular energy restoration

NAD+ is essential for mitochondrial ATP production. Restoring cellular energy is why clients report deep, sustained energy rather than a caffeine-style spike.

Sharper cognition and focus

Many clients notice improved mental clarity, faster recall, and less brain fog within 24–72 hours of their first infusion.

Better recovery and performance

NAD+ supports repair pathways used by athletes, executives, and shift workers. Faster recovery from training, illness, and stress.

Neuroprotective and anti-aging

Growing research supports NAD+ for longevity, addiction recovery, chronic fatigue, and neuroprotection. We build protocols around your goals.

DNA repair and cellular defense

NAD+ fuels the sirtuin and PARP enzymes that repair DNA damage from age, alcohol, UV exposure, and oxidative stress.

Mood and sleep quality

Clients on a loading series frequently report steadier mood and deeper sleep — likely tied to improved mitochondrial function and neurotransmitter synthesis.

Who it's for

Is NAD+ IV therapy right for you?

  • Adults over 35 experiencing fatigue, brain fog, or slower recovery
  • Athletes and executives seeking sustained energy and focus
  • Post-illness or post-COVID recovery
  • Anti-aging and longevity protocols
  • Addiction recovery support (as part of a broader plan)
  • Chronic fatigue, fibromyalgia, and long-COVID symptoms

The process

What to expect at your visit

01

Free consultation

We review your health goals, medications, and history. Baseline labs recommended for anti-aging clients.

02

Slow infusion

NAD+ must be infused slowly. We start at a comfortable rate and adjust based on how you feel — 60–90 minutes total.

03

Onset in 24–72 hrs

Most clients feel a clarity + energy shift the day after their first infusion. Effects compound with a loading series.

04

Maintenance protocol

After a loading phase, monthly (or more frequent) maintenance keeps NAD+ elevated. We schedule automatically for members.

Locations

Two South Boston clinics

IV League Hydration — L Street (East Campus)

47 L Street
South Boston, MA 02127

Mon – Tue: 10am – 6pm · Wed: Closed · Thu – Fri: 10am – 6pm · Sat – Sun: 10am – 2pm

IV League Hydration — A Street (West Campus)

36 A Street
South Boston, MA 02127

Mon – Tue: 10am – 6pm · Wed: Closed · Thu – Fri: 10am – 6pm · Sat – Sun: 10am – 2pm

Serving South Boston, Seaport, Fort Point, City Point, Dorchester Heights, the Financial District, Back Bay, Beacon Hill, the South End, the North End, Cambridge and Brookline.

Neighborhood pages:South BostonSouthie / L StreetBack BayBeacon HillSouth EndNorth EndSeaportCambridgeBrookline

Looking for a specific treatment in your neighborhood? Browse the Boston neighborhood service directory.

See our full guide to IV therapy in Boston. Mobile IV service available anywhere in Greater Boston — learn about mobile IV in Boston or see our mobile IV group events guide.

FAQ

Common questions

What is NAD+ IV therapy?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body — it's essential for energy production, DNA repair, and cellular longevity. Levels decline sharply after age 30. NAD+ IV therapy delivers a therapeutic dose directly to your cells.

How much does NAD+ IV cost in Boston?

NAD+ IV therapy at IV League starts at $425 for a single 250mg infusion. Multi-session packages ($1,600 for 4 infusions) reduce the per-visit cost significantly. Members save on every session.

How long does a NAD+ drip take?

60–90 minutes depending on your dose and tolerance. NAD+ must be infused slowly to minimize side effects — we titrate the drip rate to your comfort.

What does NAD+ feel like?

During infusion, some people experience a mild flushing, chest tightness, or nausea — this resolves quickly if we slow the drip. Afterward, most clients report increased mental clarity, energy, and mood within 24–72 hours.

Is NAD+ safe?

NAD+ has a strong safety profile when administered by licensed medical professionals. Every infusion at IV League is placed by an RN led by our Medical Director Olivia Kelly, NP, with continuous monitoring.

How often should I get NAD+?

Common protocols: a 'loading phase' of 4–10 infusions over 2–4 weeks, then monthly maintenance. Athletes and executives often continue with weekly or bi-weekly sessions. We'll design a protocol during your consult.

Who benefits most from NAD+?

Anyone over 35 experiencing fatigue, brain fog, poor recovery, or reduced athletic performance. Also strong evidence for anti-aging, addiction recovery support, neuroprotection, and chronic fatigue conditions.

NAD+ IV vs. NAD+ injections — which is better?

IV delivers the largest dose with 100% bioavailability and is the fastest way to raise cellular NAD+, but takes 60–90 minutes. IM/SC injections are a 10-minute option that works well for weekly maintenance between infusions. Most clients load with IV, then maintain with injections.

Do oral NAD+ supplements work as well?

Oral NR and NMN capsules raise NAD+ precursors modestly, but absorption is limited by first-pass liver metabolism. IV NAD+ bypasses digestion entirely, which is why the clinical effect is noticeably larger and faster.

Can I eat before a NAD+ infusion?

Yes — please do. A light meal and good hydration in the two hours before your appointment reduce nausea and lightheadedness during the drip.

Are there side effects?

The most common are transient during infusion: warmth or flushing, chest or abdominal tightness, mild nausea, and headache. All resolve within seconds to minutes when we slow the drip rate. Serious reactions are rare.

Who should not get NAD+?

We screen for pregnancy and breastfeeding, active cancer treatment, significant kidney or liver disease, and certain cardiac conditions. Your consult with our NP determines whether NAD+ is appropriate for you.

Ready to book nad+ iv therapy?

Same-week appointments available. Free consultations for weight loss and peptide clients.

Dosing

NAD+ protocols we build in Boston

Your NP sets the final plan at consult. These are the starting points we use most.

Cognitive & energy reset

Brain fog, burnout, post-illness fatigue

4 × 250mg IV over 2 weeks, then monthly maintenance

Longevity / anti-aging

Adults 40+ focused on healthspan

Loading pack of 4, then 250mg IV monthly + weekly IM

Athletic recovery

Endurance and strength athletes in-season

250mg IV every 2 weeks, IM on hard training weeks

Recovery support

Sobriety and neuro-recovery programs

Higher-dose extended infusions on a physician-guided schedule

Before your visit

How to prep for NAD+

  • Eat a light meal 1–2 hours before — an empty stomach makes nausea more likely.
  • Hydrate well the day before and the morning of your infusion.
  • Bring a list of medications and supplements for your NP review.
  • Plan for 60–90 minutes in the chair; bring headphones, a laptop, or a book.
  • Skip alcohol for 24 hours before and after to protect the effect.

Pairs well with

Stack your NAD+ visit