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I.V. League Hydration

Niagen® IV Infusions

$699

Experience the Future of NAD+ Boosting

Unlock the full potential of your cellular health with our new in-home Niagen® IV infusions. This cutting-edge treatment brings the gold standard in NAD+ boosting directly to your home.

HSA/FSA Eligible

Questions? Call us at 1-800-905-4252

Niagen IV therapy infusion bag at IV League Hydration

Niagen is the patented form of nicotinamide riboside (NR), a direct precursor to NAD+. NAD+ fuels every cell in your body: it powers mitochondria, activates DNA repair, and supports the sirtuin pathways linked to longevity and resilience. NAD+ levels decline by roughly 50% by age 40, which contributes to fatigue, slower recovery, brain fog, and visible aging. Oral Niagen supplements exist, but digestion and first-pass liver metabolism limit how much reaches your cells. Niagen IV therapy bypasses the gut entirely, delivering the precursor directly into circulation so your body can convert it into NAD+ quickly and efficiently. IV League Hydration offers Niagen IV in South Boston as a standalone cellular-health infusion or as an add-on to our performance, beauty, and recovery drips.

Pricing

Transparent pricing

Niagen IV infusion

$699

Per infusion — standalone or add-on to any signature drip

Performance + Niagen

Package

Hydration, magnesium, B-complex + Niagen

The Knockout + Niagen

Package

Glutathione, biotin, vitamin C + Niagen

HSA/FSA accepted. Ask about membership pricing.

Benefits

Why patients choose Niagen IV therapy

Clean cellular energy

Niagen supports NAD+ production, which mitochondria need to make ATP — the energy currency of every cell. Many clients notice steadier energy without the jitters of stimulants.

Mental clarity & focus

NAD+ is critical for neuronal health and cognitive resilience. Niagen IV is popular with executives, students, and anyone fighting brain fog.

Recovery & longevity

By raising NAD+, Niagen supports DNA repair, sirtuin activation, and muscle recovery — making it a favorite among athletes and anti-aging clients.

Better than oral bioavailability

IV delivery bypasses the digestive tract and liver, giving cells faster access to the NAD+ precursor compared to capsules or powders.

Who it's for

Is Niagen IV therapy right for you?

  • Low energy or chronic fatigue
  • Brain fog and cognitive decline
  • Athletes seeking faster recovery
  • Longevity and healthy-aging protocols
  • Poor tolerance for high-dose NAD+ IV
  • Clients wanting to stack with other drips
  • Post-viral recovery and long-COVID support

The process

What to expect at your visit

01

Book a consultation

Schedule online at our 47 L Street or 36 A Street clinic, or request mobile IV service across Greater Boston.

02

Nurse screening

A licensed RN reviews your health history, medications, and goals to confirm Niagen IV is appropriate and select the right dose.

03

Infusion

Niagen IV takes 30–60 minutes depending on dose. You can relax, read, or work while the infusion runs.

04

Build the protocol

Most clients start with weekly sessions for 4–6 weeks, then maintain monthly. We adjust the plan based on your response.

Locations

Two South Boston clinics

IV League Hydration — L Street (East Campus)

47 L Street
South Boston, MA 02127

Mon – Tue: 10am – 6pm · Wed: Closed · Thu – Fri: 10am – 6pm · Sat – Sun: 10am – 2pm

IV League Hydration — A Street (West Campus)

36 A Street
South Boston, MA 02127

Mon – Tue: 10am – 6pm · Wed: Closed · Thu – Fri: 10am – 6pm · Sat – Sun: 10am – 2pm

Serving South Boston, Seaport, Fort Point, City Point, Dorchester Heights, the Financial District, Back Bay, Beacon Hill, the South End, the North End, Cambridge and Brookline.

Neighborhood pages:South BostonSouthie / L StreetBack BayBeacon HillSouth EndNorth EndSeaportCambridgeBrookline

Looking for a specific treatment in your neighborhood? Browse the Boston neighborhood service directory.

See our full guide to IV therapy in Boston. Mobile IV service available anywhere in Greater Boston — learn about mobile IV in Boston or see our mobile IV group events guide.

FAQ

Common questions

What is Niagen IV therapy?

Niagen IV therapy delivers nicotinamide riboside (NR) — a direct NAD+ precursor — directly into the bloodstream. Unlike oral supplements, IV bypasses digestion and liver metabolism, reaching cells quickly to support cellular energy, recovery, and healthy aging.

How is Niagen different from NAD+ IV?

NAD+ is the active molecule your cells use. Niagen (nicotinamide riboside) is a stable precursor your body converts into NAD+. Many clients tolerate Niagen IV as well or better than high-dose NAD+ while still raising NAD+ levels effectively.

What are the benefits of Niagen IV?

Clients report more steady energy, better mental clarity, faster workout recovery, improved sleep quality, and a general sense of resilience. Niagen supports the same cellular pathways as NAD+ — mitochondrial repair, DNA repair, and sirtuin activation — through a precursor pathway.

How much does Niagen IV therapy cost?

A single Niagen IV infusion is $699. Add it to a signature drip or stack with Performance or The Knockout packages for custom pricing. Members receive an automatic 10% discount.

How often should I get Niagen IV?

For a boost, many clients start with a single session or weekly sessions for 4–6 weeks, then move to monthly maintenance. Athletes, executives, and clients focused on longevity often use it as part of a monthly cellular health protocol.

Is Niagen IV safe?

Niagen (nicotinamide riboside) has a strong safety profile in clinical studies and is generally well tolerated. IV League's Niagen protocol is administered by licensed nurses under medical supervision, with a brief health screen before the first infusion.

What is Lactated Ringer's and why do you use it?

Lactated Ringer's (LR) is a sterile, balanced crystalloid IV fluid that contains sodium, chloride, potassium, calcium, and sodium lactate in concentrations close to your own blood plasma. It's the same fluid used in hospitals and emergency departments. We use Lactated Ringer's as the base fluid in our IV drips because the added electrolytes and lactate buffer replace what you actually lose through sweat, illness, vomiting, or alcohol — not just water and salt.

How is Lactated Ringer's different from normal saline?

Normal saline is 0.9% sodium chloride in water — sodium and chloride only. Lactated Ringer's adds potassium and calcium and includes lactate, which the liver converts to bicarbonate to help buffer acidity. Because its chloride level is closer to plasma, LR is generally considered gentler for larger-volume rehydration. Both are sterile, pharmaceutical-grade fluids; we chose LR as the standard base for our drips.

When is Lactated Ringer's used?

Clinically, Lactated Ringer's is used whenever fluid and electrolyte losses need to be replaced together — dehydration, hangover and GI-related fluid loss, heat and endurance exertion, illness with fever or vomiting, and post-procedure recovery. In our clinics it's the base for hydration and vitamin drips, and your nurse selects the volume and any add-ins for your visit under our Medical Director's standing protocols.

How is a Lactated Ringer's IV administered by a clinician?

A licensed registered nurse reviews your intake and vitals, confirms there are no contraindications, then places a small IV catheter — usually in the forearm or hand — using single-use sterile supplies and aseptic technique. The Lactated Ringer's bag is spiked with a fresh IV set, primed, and infused by gravity at a nurse-set rate, typically 30–60 minutes for a liter. Any vitamins, minerals, or medications ordered under protocol are added to the bag or given as a slow IV push. Your nurse stays with you and monitors you throughout, then removes the catheter and applies a dressing at the end.

Is a full liter of Lactated Ringer's always given?

No — the volume is a clinical decision. Most standard drips are 1 liter, but your nurse may run a smaller volume or a slower rate based on your size, vitals, medical history, and how you're tolerating the infusion. If anything changes during your visit, the nurse can slow or stop the infusion at any time.

Who should not receive Lactated Ringer's?

Lactated Ringer's may not be appropriate if you have significant kidney or liver disease, congestive heart failure, high potassium or calcium levels, or if you take medications that affect electrolyte balance. It's also not compatible with certain drugs in the same line. That's why every visit begins with a nurse-led intake and screening — if LR isn't right for you, we'll say so and refer you to your physician rather than proceed.

Can I give myself Lactated Ringer's or any IV drip at home?

No. IV therapy, including Lactated Ringer's, must be administered by a licensed healthcare professional in a clinical setting. At IV League Hydration, every infusion is started and monitored by a registered nurse under protocols directed by our Medical Director. This information is clinician-reviewed for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment. Do not attempt IV therapy at home.

Ready to book niagen iv therapy?

Same-week appointments available. Free consultations for weight loss and peptide clients.